CEO
Seth Lederman, MD
*Co-Founder, President, CEO, and Chairman of Tonix Pharmaceuticals Holding Corp. (NASDAQ: TNXP)*[[2]](https://www.tonixpharma.com/seth-lederman/)[[1]](https://en.wikipedia.org/wiki/Seth_Lederman)
Seth Lederman (born July 30, 1957) is an American physician, scientist, and entrepreneur who founded Tonix Pharmaceuticals in 2007 and has served as its President since 2010 and Chairman since inception, becoming President, CEO, and Chairman of the board in October 2011.[[1]](https://en.wikipedia.org/wiki/Seth_Lederman)[[2]](https://www.tonixpharma.com/seth-lederman/)[[3]](https://www.biotech2050.com/episodes/lederman-sept2020-4kl5l) Prior to Tonix, he founded Targent Pharmaceuticals, which developed levoleucovorin (marketed as Fusilev by Spectrum Pharmaceuticals after acquisition), and co-founded Konanda Pharma Partners, along with operating companies Validus and Fontus Pharmaceuticals.[[1]](https://en.wikipedia.org/wiki/Seth_Lederman)[[3]](https://www.biotech2050.com/episodes/lederman-sept2020-4kl5l) From 1985 to 2017, Dr. Lederman was faculty at Columbia University's College of Physicians and Surgeons, rising to Associate Professor of Medicine in 1996 and directing the Laboratory of Molecular Immunology, with research in molecular immunology, infectious diseases, HIV, and autoimmune therapeutics, including pioneering work on CD40-Ligand (CD154).[[3]](https://www.biotech2050.com/episodes/lederman-sept2020-4kl5l)
Dr. Lederman earned an AB in Chemistry *cum laude* from Princeton University in 1979 and an MD from Columbia University in 1983, followed by training in internal medicine and rheumatology at Columbia Presbyterian Hospital as an NIH Physician-Scientist (1985-1990).[[3]](https://www.biotech2050.com/episodes/lederman-sept2020-4kl5l) Under his leadership at Tonix, a clinical-stage biopharmaceutical company focused on CNS disorders, key developments include TNX-102 SL (TONMYA™ conditionally accepted by FDA in January 2024 for fibromyalgia) and a positive Phase 3 trial in December 2023.[[1]](https://en.wikipedia.org/wiki/Seth_Lederman)[[5]](https://www.youtube.com/watch?v=hB1eOZQAjhE)[[6]](https://www.youtube.com/watch?v=F3PGanR7u2Y) As a corporate insider and CEO, he has overseen recent trading activities at TNXP.[user_query]
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