InsiderSignal.AI

InsiderSignal.ai

OBIO - Orchestra Biomed Holdings, Inc.

Insider Purchase by Perceptive Advisors LLC (10%)

1 Year
After Trade
Before Trade

Loading data...

Trade Summary

6 months ago, Perceptive Advisors LLC, serving as 10% owner at Orchestra Biomed Holdings, Inc. (OBIO), purchased 700,000 shares at $2.75 per share, for a total transaction value of $1,925,000.00. Following this transaction, Perceptive Advisors LLC now holds 5,292,556 shares of OBIO.

This purchase represents a 15.00% increase in Perceptive Advisors LLC's stake in the company. This is considered a high-conviction trade given the significant change in ownership.

The trade was executed on Friday, August 1, 2025 and publicly disclosed via SEC Form 4 filing on Tuesday, August 5, 2025, 4 days after the trade was made.

Orchestra Biomed Holdings, Inc. operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider buying activity in this sector can provide valuable signals about industry trends and company-specific developments.

Perceptive Advisors LLC

Perceptive Advisors LLC

10%

Perceptive Advisors LLC is a New York-based investment firm founded in July 1999 by Joseph Edelman, specializing in public and private investments in the healthcare, biotechnology, and life sciences sectors.[[1]](https://mtec-sc.org/investors/perceptive-advisors-llc)[[2]](https://en.wikipedia.org/wiki/Perceptive_Advisors)[[3]](https://www.perceptivelife.com) Managing approximately $8 billion in assets, the firm employs a high-risk strategy focused on small and mid-cap companies, offering venture capital through the Perceptive Xontogeny Venture Fund for early-stage life sciences, customized debt financing via the Perceptive Credit Opportunities Fund, and later-stage investments through the Perceptive Discovery Fund.[[1]](https://mtec-sc.org/investors/perceptive-advisors-llc)[[2]](https://en.wikipedia.org/wiki/Perceptive_Advisors)[[4]](https://fintel.io/i/perceptive-advisors-llc) Key leadership includes CEO and Portfolio Manager Joseph Edelman, Chief Investment Officer Adam Stone, and Managing Director Michael Altman.[[1]](https://mtec-sc.org/investors/perceptive-advisors-llc) Perceptive Advisors has a notable portfolio including holdings in companies like Verona Pharma (19.31% of portfolio), Ascendis Pharma, Arcellx, Rhythm Pharmaceuticals, and Nuvalent, with recent activity such as trading at Orchestra Biomed Holdings, Inc. (OBIO) as a 10% corporate insider.[[4]](https://fintel.io/i/perceptive-advisors-llc)[[6]](https://whalewisdom.com/filer/perceptive-advisors-llc) The firm faced challenges, including losses exceeding 40% in 2021-2022—its worst in history—and a $1.5 million SEC fine in 2022 for undisclosed SPAC conflicts, but maintains a strong track record with only two negative return years since inception prior to recent downturns.[[2]](https://en.wikipedia.org/wiki/Perceptive_Advisors)

View full insider profile →

Trade Price

$2.75

Quantity

700,000

Total Value

$1,925,000.00

Shares Owned

5,292,556

Trade Date

Friday, August 1, 2025

205 days ago

SEC Filing Date

Tuesday, August 5, 2025

Filed 4 days after trade

HEALTHCAREBIOTECHNOLOGY

About Orchestra Biomed Holdings, Inc.

Company Overview

No company information available
View news mentioning OBIO

💬 Want Deeper Insight?

Use our AI assistant to ask questions about this trade, the insider, or the company.

Chat with AI

Share this trade

https://insidersignal.ai/trade/105821

🚀 Track Insider Trades in Real-Time

Create a free account to access our full database of insider trades, AI-powered analysis, price alerts, and discover what corporate executives are buying and selling.

Create Free AccountLearn More

✓ Free forever plan available  •  ✓ No credit card required  •  ✓ Cancel anytime